You can install ThingWorx core 8.0 on Windows 2008 and you can install ThingWorx Analytics 8.0 on Windows 10.
However you may not be able to install inside a Virtual machine. The reason is that ThingWorx Analytics requires docker.
Docker on Windows uses some virtualization feature that I don't think you will be able to use inside a VM. You probably need to run on a physical Windows 10 machine.
If you need to run in a VM, then use a Linux based version for ThingWorx Analytics so that docker can run on it.
Hope this helps
Thanks for the answer!
i have a further question, now i'am thinking on 2 installation options.
It is better if i install THingworx Core on Windows 2008 VM and Analytics on CentOS VM or both on 2 different CentOS VM?
PTC, if you know, which configuration suggests? Or both configuration are the same?